Streptococcus pneumoniae pneumonia complicated with bloodstream infection
Conditions
Interventions
Bloodstream infection group:None
Non-bloodstream infection group:None
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 16 Years
Inclusion criteria
Inclusion criteria: 1.Age >=1 month and < < 16 years old; 2.A hospitalized child was diagnosed with Streptococcus pneumoniae pneumonia, meeting the standards of the "Guidelines for the Management of Community-Acquired Pneumonia in Children". The etiological diagnosis was confirmed (Streptococcus pneumoniae was detected in sputum or alveolar lavage fluid culture, or the nucleic acid test of Streptococcus pneumoniae was positive), and the clinical diagnosis was confirmed (typical clinical manifestations of pneumonia + lung imaging evidence). 3.The clinical data are complete.
Exclusion criteria
Exclusion criteria: 1.Pneumonia complicated with other bacteria such as Staphylococcus aureus and Haemophilus influenzae, or non-viral pathogens such as Mycoplasma pneumoniae, chlamydia, and fungi; 2.Antibiotics were used before admission; 3.Abnormal immune function, including congenital immune deficiency diseases, AIDS, long-term use of glucocorticoids/immunosuppressants, after hematopoietic stem cell transplantation, chemotherapy period for malignant tumors, etc; 4.Combined with underlying severe diseases, including complex congenital heart disease, bronchopulmonary dysplasia, end-stage renal disease, liver cirrhosis, neuromuscular diseases, genetic metabolic diseases and other diseases that significantly affect the prognosis of infection; 5.Non-infectious lung diseases, such as atelectasis, bronchial foreign bodies, allergic pneumonia and other cases misdiagnosed as pneumonia; 6.Infection caused by iatrogenic factors, secondary infection after admission due to central venous catheterization, tracheal intubation and other operations, rather than bloodstream infection directly progressing from Streptococcus pneumoniae pneumonia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laboratory indicators: blood routine, blood biochemistry, procalcitonin, and pathogen results of blood culture;Chest imaging indicators; | — |
Countries
China
Contacts
Public ContactXia Xiaojiao
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed