postoperative residual neuromuscular blockade
Conditions
Interventions
GA group:General anesthesia+deep neuromuscular blockade
PVB group:Paravertebral nerve block general anesthesia moderate neuromuscular blockade
Sponsors
Xiangya Second Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years, any gender; 2. BMI 18-30 kg/m^2; 3. ASA grade I-III, planning to undergo laparoscopic surgery; 4. Understand this study and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Participants unwilling to participate in the study or those who withdraw midway; 2.Participants unable to cooperate due to accompanying mental illness or impaired consciousness; 3.those with incomplete clinical data; 4.Those allergic to muscle relaxants, opioids, and anesthetic drugs; 5.Patients with severe cardio-pulmonary diseases, severe hepatic or renal dysfunction; patients with abnormal neuromuscular function; 6.Infection, tumor, severe anatomical variation due to severe deformity, severe coagulopathy, and other contraindications related to nerve block at uncture site; 7.Those intolerant to this study; 8.Participated in another clinical trial within 3 months prior to enrollment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications (pulmonary infection, atelectasis, hypoxemia,);Intraoperative hemodynamic changes;Postoperative extubation time;PACU length of stay;Surgical field condition score;Number of times intra-abdominal pressure was increased during surgery; | — |
Countries
China
Contacts
Public ContactXu junmei
Xiangya Second Hospital of Central South University
Outcome results
None listed