Port wine stain, PWS
Conditions
Interventions
Pingyangmycin Injection Group:Intralesional interstitial injection of Pingyangmycin
Control Group:An equal volume of placebo mixture
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
8 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Patients with facial and lip enlargements and asymmetrical deformities associated with port-wine stains who meet the diagnostic criteria for vascular malformations in the guidelines for hemangioma and vascular malformation treatment, and have been confirmed by at least three clinicians. 2. Aged 8-50 years (including 8 and 50), any gender; 3. Have not received any other injection treatments in the past 3 months;
Exclusion criteria
Exclusion criteria: 1. People with facial infections, a history of skin cancer, weakened immune systems, or poor wound healing; 2. Women who are pregnant or breastfeeding; 3. Those with serious heart, brain, lung, liver, or kidney problems, a history of mental illness, or recent history of heavy drinking or drug abuse; 4. Participants who don’t want to sign the informed consent form or won’t cooperate with medical staff; 5. Patients currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of reduction in hypertrophic lesion volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Micro-ultrasound detection of lesion thickness and blood flow;3D scanning to evaluate surface volume;Visual Analog Scale (VAS) scoring method;Objective detection of lesion color using a photometer; | — |
Countries
China
Contacts
Public ContactMa Gang
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed