Amyloidosis(AL)
Conditions
Interventions
Newly Diagnosed AL Amyloidosis Patient Group:None
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18, = 3 months, and at least 1 year of follow-up can be completed.
Exclusion criteria
Exclusion criteria: 1. Merge other active malignant tumors (excluding basal cell carcinoma and cervical cancer in situ); 2. Previously received hematopoietic stem cell transplantation or CAR-T therapy; 3. Serious uncontrolled infections (active tuberculosis, HIV positive with CD4 <200/µ L, etc.); 4. NYHA grade IV or left ventricular ejection fraction <30%; 5. Pregnant or lactating women; 6. Unable to cooperate with follow-up due to mental illness or cognitive impairment; 7. Researchers have determined that bone marrow puncture is not suitable (due to severe coagulation disorders, anatomical abnormalities at the puncture site, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD9; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP, Troponin, 24-hour urinary protein, creatinine clearance rate, bone marrow plasma cell ratio, lactate dehydrogenase, ß 2-microglobulin, albumin, hemoglobin, platelets; | — |
Countries
China
Contacts
Public ContactQiang Zhuang
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed