Biliary and pancreatic diseases
Conditions
Interventions
HFNC Group:high-flow nasal oxygen (HFNO)
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Scheduled to undergo elective ERCP, which will be performed under sedation (non-intubated) anesthesia. 2.Assessed as frail, with a Clinical Frailty Scale (CFS) score >= 4. 3.Preoperative pulse oximetry SpO2 >= 94% (while breathing room air). 4.Expected to receive intravenous sedation with spontaneous breathing maintained during the procedure (non-intubated general anesthesia) and able to safely tolerate HFNC or nasal cannula oxygen therapy. 5.The patient or their legal representative understands the study content and provides written informed consent.
Exclusion criteria
Exclusion criteria: 1.Inability to tolerate or contraindications to using nasal oxygen therapy devices (e.g., severe nasal deformity, active severe epistaxis, recent nasal/sinus surgery, etc.). 2.Recent (within the past 3 months) participation in other interventional clinical trials. 3.Severe impairment of mental/cognitive status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of intraoperative hypoxia events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lowest SpO2 during surgery;Incidence of breathing-related interventions;ERCP surgery interruption rate;Postoperative lung complication rate; | — |
Countries
China
Contacts
Public ContactXifeng Wang
The First Affiliated Hospital of Nanchang University
Outcome results
None listed