Chronic hepatitis B virus infection
Conditions
Interventions
Group with elevated HBV DNA:none
HBV DNA non-elevated group:none
Sponsors
The Third Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Diagnosed with chronic hepatitis B (HBsAg positive =6 months) before pregnancy or in early pregnancy (=28 weeks, at least two before delivery). 4. Pregnancy resulted in a live birth. 5. Complete clinical data, and the infant completed HBsAg/HBsAb testing at >=7 months of age.
Exclusion criteria
Exclusion criteria: 1. Co-infection with other viral hepatitis (HCV, HDV, HEV, etc.) or HIV infection. 2. Complicated with decompensated cirrhosis, liver cancer, or severe liver disease. 3. Miscarriage, stillbirth, neonatal death. 4. Infants who have not completed HBsAg/HBsAb testing at >=7 months of age.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mother-to-child transmission; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function (ALT); | — |
Countries
China
Contacts
Public ContactXingfei Pan
The Third Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed