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Association between Levels of Exposures in Follicular Fluid and the Occurrence of Reproductive Disorders

Effects of Follicular Fluid Microenvironment on Oocyte Quality and Pregnancy Outcomes in Patients with Female Reproductive Disorders and the Underlying Mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600128065
Enrollment
Unknown
Registered
2026-07-13
Start date
2026-07-14
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility

Interventions

Young and healthy women group:None
Polycystic ovary syndrome group:None
Group with decreased ovarian reserve function:None

Sponsors

Women’s Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Body mass index (BMI): 18–25 kg/m^2; 2.Number of retrieved oocytes >= 1;

Exclusion criteria

Exclusion criteria: 1.Chromosomal abnormalities; 2.Uterine malformations, intrauterine adhesions; 3.History of ovarian surgery or pelvic radiotherapy/chemotherapy; 4.Positive infectious disease screening, autoimmune or metabolic diseases;

Design outcomes

Primary

MeasureTime frame
Whether related diseases occur and the levels of environmental exposures;

Secondary

MeasureTime frame
Clinical information (including the female's age, height, weight, BMI, duration and type of infertility, ART history, basic endocrine (FSH, LH, E2, P on the 2nd and 3rd days of menstruation), AMH, AFC, ovulation induction protocol, days and dosage of Gn, Trigger day hormone levels (E2, P, LH), oocyte retrieval date, number of retrieved oocytes, oocyte maturation rate (MII oocyte rate), fertilization rate, high-quality embryo rate (D3 cleavage-stage embryos or D5 blastocysts), available embryo ra;

Countries

China

Contacts

Public ContactLv Pingping

Women’s Hospital, Zhejiang University School of Medicine

lvpingping@zju.edu.cn+86 571 87061501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026