Patients with Parkinson’s disease undergoing DBS surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the Chinese diagnostic criteria for Parkinson’s disease (PD); 2. Aged >= 18 years old; 3. Underwent bilateral subthalamic nucleus deep brain stimulation (STN-DBS) or globus pallidus interna deep brain stimulation (GPi-DBS); 4. Complete preoperative and postoperative cognitive function assessment records available in medical charts.
Exclusion criteria
Exclusion criteria: 1. Preoperative severe dementia (defined as Montreal Cognitive Assessment (MoCA) score < 20 or clinical diagnosis of dementia); 2. Concomitant other severe neurological diseases or severe unstable internal medical illnesses; 3. Incomplete medical records that preclude judgment of the primary outcome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Perioperative Neurocognitive Disorder (PND); | — |
Countries
China
Contacts
Nanjing Brain Hospital