Stroke
Conditions
Interventions
Sham stimulation group:Rehabiliation combined with sham stimulation
Transcutaneous spinal cord stimulation group:Rehabilitation combined with transcutaneous spinal cord stimulation
Sponsors
Beijing Tsinghua Changgung Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with stroke by cranial CT or MRI, including cerebral infarction, cerebral hemorrhage, and cerebral embolism; 2. Aged 18–75 years, with first-ever stroke and a disease duration of 1–6 months; 3. Obvious unilateral lower-limb motor impairment, with the ability to complete gait-related assessments and training independently or with assistance; 4. No significant lower-limb spasticity, defined as a lower-limb Modified Ashworth Scale score <1; 5. No severe cognitive or language impairment; 6. Willingness to participate in the trial and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Comorbid other neurological diseases; 2. Obvious language impairment, cognitive impairment, hemispatial neglect, or psychiatric disorders that prevent cooperation with training and assessments; 3. History of epilepsy; 4. Comorbid fractures or other conditions affecting lower-limb motor function; 5. Significant sensory impairment in the lower back or lower limbs; 6. Obvious skull defect or other factors that may interfere with EEG signal acquisition during training; 7. Inability to cooperate with treatment or examinations for other reasons; 8. Participation in other clinical trials or receipt of spinal cord stimulation therapy within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| walking time at 10 Minutes Walking Test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Movement-related event-related desynchronization/synchronization (ERD/ERS);Intermuscular coherence;Fugl-Meyer for lower limb;beta-band corticomuscular coherence;Functional Ambulation Catergory;Berg Balance Scale; | — |
Countries
China
Contacts
Public ContactPan Yu
Beijing Tsinghua Changgung Hospital
Outcome results
None listed