Congenital heart disease encompasses ventricular septal defect, atrial septal defect, patent ductus arteriosus, tetralogy of Fallot, double outlet right ventricle, transposition of the great arteries, persistent arterial trunk, endocardial cushion defect, single ventricle, and Ebstein anomaly
Conditions
Interventions
case series:None
Sponsors
The Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Congenital heart diseases include ventricular septal defect (VSD), atrial septal defect (ASD), patent ductus arteriosus (PDA), tetralogy of Fallot (TOF), double outlet right ventricle (DORV), transposition of the great arteries (TGA), persistent arterial trunk (TA), pulmonary stenosis (PS), endocardial cushion defect (ECD), single ventricle (SV), and Ebstein anomaly. 2. Aortic root pathologies include aortic sinus aneurysm (ruptured or unruptured), bicuspid aortic valve, aortic valve prolapse, aortic root dilation or aneurysm (Z-score >= 2), Type A aortic dissection involving the root, infective endocarditis-induced aortic root abscess or perivalvular leakage, Marfan syndrome, and other related conditions. 3. Mixed or joint pathologies are also encountered. These include aortic sinus aneurysm rupture complicated by ventricular septal defect, aortic sinus aneurysm rupture combined with aortic valve prolapse or a bicuspid aortic valve, and bicuspid aortic valve with concomitant aortic root dilation. 4. Ultrasound images are complete and traceable, with ultrasound report completeness =80% (for retrospective data).
Exclusion criteria
Exclusion criteria: 1.Isolated coronary artery disease, cardiomyopathy, pericardial diseases, cardiac tumors (excluding CHD or ARD); 2.The ultrasound image quality is poor, making it impossible to measure key parameters; 3.Clinical data missing; 4.Patients or legal guardians who explicitly refuse data use for research or are unable to complete follow-up (applicable only to the prospective component).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary composite endpoint (All-cause mortality, heart transplantation, reoperation/interventional therapy, hospitalization for heart failure, infective endocarditis, aortic diss); | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: NYHA worsening =1 class, new-onset arrhythmia, pulmonary hypertension progression, echocardiographic parameter deterioration.; | — |
Countries
China
Contacts
Public ContactChen Rong
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed