Low vision and amblyopia
Conditions
Interventions
The low vision and amblyopia observation group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 3 years old to 75 years old (inclusive), gender not limited. 2.Due to various reasons, patients with low vision ranging from 0.05 to 0.3 (ETDRS visual acuity or LogMar visual acuity) or patients with amblyopia. 3.Have basic understanding and communication skills, and be able to follow research instructions. The Mini-Mental State Examination (MMSE) score is >=24 points. Be able and willing to complete all research procedures. 4.Patients with low vision or amblyopia who are about to undergo visual function training and have purchased or leased research training equipment on their own. Voluntarily participating in this study, understanding the purpose, process, potential risks and benefits of the study, and having signed the written informed consent approved by the BioMedical Research Ethics Committee of the Affiliated Eye and Vision Hospital of Wenzhou Medical University.
Exclusion criteria
Exclusion criteria: 1.Combining other unstable and progressive ocular diseases may significantly affect the completion of training tasks or the interpretation of assessment results. This includes, but is not limited to: active ocular inflammation (such as uveitis), uncontrolled glaucoma, macular edema with clinical significance, and severe cataracts. 2.There are clear cases of visual neglect, agnosia, apraxia, or patients suffering from severe mental illness, cognitive impairment, dementia (MMSE score < 24), and those who, in the judgment of the researchers, are unable to understand and cooperate with the research procedures. 3.Has a history of epilepsy, or is sensitive to flashing lights and rapidly moving graphic patterns, and has a risk of photosensitive seizure. 4.In the past six months, one has participated in other formal and systematic visual rehabilitation training or related clinical trials to avoid confusion with the research measures. 5.The researchers determined that there were no other circumstances that might put the subjects at high risk or interfere with the smooth progress of the study and the interpretation of the results (such as severe cardiovascular or cerebrovascular diseases, an expected lifespan of less than one year, alcoholism or drug abuse, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between training parameters and rehabilitative efficacy;Safety indicators;Visual Impairment Quality of Life Questionnaire (Modified Version);Contrast sensitivity;Visual Function and Quality of Life Questionnaire (NEI VFQ-25); | — |
Countries
China
Contacts
Public ContactJun Jiang
Eye Hospital, Wenzhou Medical University
Outcome results
None listed