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Clinical studies on the effects of exercise intervention on functional performance in patients with sarcopenia

Clinical studies on the effects of exercise intervention on functional performance in patients with sarcopenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127981
Enrollment
Unknown
Registered
2026-07-11
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis, sarcopenia,Osteosarcopenia

Interventions

Experimental group:Balance training, resistance training, Baduanjin (Eight Pieces of Brocade) training, core stability training
Control group:Health education

Sponsors

Wuhan Sports University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged >=60 years and -2.5 and <=-1.0 at any measured site; (2) Osteoporosis defined as a T-score <=-2.5 at any measured site; 4.Diagnosed with sarcopenia, defined as low appendicular skeletal muscle mass combined with reduced muscle strength and/or impaired physical performance; 5.Appendicular skeletal muscle mass measured using DXA, with the appendicular skeletal muscle index (ASMI) calculated as appendicular skeletal muscle mass divided by height squared. Low muscle mass is defined as: (1) ASMI<7.0 kg/m^2 for men; (2) ASMI<5.5 kg/m^2 for women; 6.Able to complete basic low-to-moderate intensity exercise training with safety supervision or assistance when necessary; 7.Able to use a smartphone and WeChat for study communication, exercise management, and follow-up; 8.Able to understand the study objectives, procedures, potential benefits, and risks, and willing to participate voluntarily; 9.Able and willing to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1.A fragility fracture, major trauma, or musculoskeletal surgery within the previous 6 months; 2.Severe cardiovascular or respiratory disease that may increase exercise-related risk or interfere with implementation of the exercise intervention; 3.Severe neurological, hepatic, renal, endocrine, or metabolic disease that may affect study outcomes, exercise safety, or adherence; 4.Severe visual impairment, vestibular dysfunction, or another condition that substantially affects balance, walking ability, or exercise safety; 5.Severe cognitive impairment, psychiatric disorder, or communication impairment that prevents understanding of the study requirements, participation in the intervention, or completion of outcome assessments; 6.Secondary osteoporosis clearly caused by malignant tumors, radiotherapy, chemotherapy, long-term glucocorticoid use, or another severe endocrine or metabolic disorder; 7.Neurogenic low back pain, severe spinal stenosis, spinal cord or nerve root compression, or another spinal disorder requiring surgical treatment; 8.Severe joint pain, marked limitation of movement, or another contraindication to exercise that prevents safe completion of the prescribed training program; 9.Current participation in another interventional clinical study or receipt of a systematic and structured exercise or rehabilitation program that may influence the study outcomes; 10.Inability to maintain the existing anti-osteoporosis medication regimen during the study, or an anticipated need for additional treatment that may substantially affect the study outcomes; 11.Considered unsuitable for participation by the research team or treating physician based on the participant’s overall health status.

Design outcomes

Primary

MeasureTime frame
Changes in bodily functions;

Secondary

MeasureTime frame
Pain intensity;Activities of daily living;Bone density;Balance ability;Muscle mass;Health-related quality of life;

Countries

China

Contacts

Public ContactWeitao Zheng

Wuhan Sports University

zhengweitao@sina.com+86 27 8719823

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026