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Efficacy of Repetitive Transcranial Magnetic Stimulation for Comorbid Chronic Neck Pain and Insomnia: A Randomized, Double-Blind, Sham-Controlled Trial

Efficacy of Repetitive Transcranial Magnetic Stimulation for Comorbid Chronic Neck Pain and Insomnia: A Randomized, Double-Blind, Sham-Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127979
Enrollment
Unknown
Registered
2026-07-11
Start date
2026-07-15
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comorbid Chronic Neck Pain and Insomnia

Interventions

M1-rTMS:Including primary motor cortex transcranial magnetic stimulation and neck function training.
DLPFC-rTMS:Including dorsolateral prefrontal cortex transcranial magnetic stimulation and neck function training.
Sham-rTMS:Including sham transcranial magnetic stimulation and neck function training.

Sponsors

Beijing Sport University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 65 years old; 2. Persistent or recurrent neck pain and limited mobility for >= 3 months; 3. Pain intensity in the Visual Analogue Scale (VAS) >= 3; 4. Diagnosed with insomnia: Evaluated by the Brief Insomnia Questionnaire and meeting the diagnostic criteria for insomnia disorder in the 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5); 5. Pittsburgh Sleep Quality Index (PSQI) > 7 points; 6. Insomnia Severity Index (ISI) > 10 points.

Exclusion criteria

Exclusion criteria: 1. With specific causes of neck pain (such as malignant tumors, spinal arthritis, spinal fractures); 2. Pregnant or breastfeeding; 3. Previously undergone spinal surgery; 4. Suffering from inflammatory or autoimmune diseases; 5. Having other clinical diagnosed sleep disorders (such as sleep apnea, restless legs syndrome); 6. Self-reported having a history of mental, neurological or physical diseases directly related to insomnia episodes (such as substance abuse, alcohol abuse, inflammatory diseases); 7. Starting new treatment for insomnia or pain within the past month; 8. Having contraindications for rTMS (such as severe head trauma, intracranial hypertension, implanted ferromagnetic devices, history of epilepsy).

Design outcomes

Primary

MeasureTime frame
Neck Disability Index;Pittsburgh Sleep Quality Index;—

Secondary

MeasureTime frame
Visual Analog Scale;Insomnia Severity Index;Hospital Anxiety and Depression Scale ;Deep neck flexor endurance;Pressure Pain Threshold;Heart Rate Variability;Functional Near-Infrared Spectroscopy;—

Countries

China

Contacts

Public ContactXinrong Wang

Beijing Sport University

wangxinrong2024@163.com+86 10 6296 8094

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026