Postpartum Depression (PPD)
Conditions
Interventions
Sham ta-VNS group:Subjects in the sham stimulation group underwent identical operational procedures with electrodes placed over the left cymba conchae. After completion of the same intensity titration
Ta-VNS group:Subjects in the stimulation group received transcutaneous auricular vagus nerve stimulation applied to the left cymba conchae at a frequency of 40 Hz and a pulse width of 300 µs, delivere
Sponsors
Changzhi Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 45 years inclusive. 2. Gestational age >= 37 weeks. 3. American Society of Anesthesiologists physical status classification (ASA): Grade I–II. 4. Pre-pregnancy body mass index (BMI): 20 kg/m² <= BMI <= 35 kg/m². 5. Capable of understanding the study protocol and all assessment scales, and able to communicate effectively with research staff. 6. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to neuraxial anesthesia, or those who decline neuraxial anesthesia and require cesarean delivery under general anesthesia. 2. Emergency cesarean section. 3. Presence of severe gestational complications (e.g., severe preeclampsia, placenta accreta spectrum, HELLP syndrome, placenta previa, placental abruption, etc.). 4. Refractory hypertension, severe cardiovascular diseases (New York Heart Association functional class = ?), hyperthyroidism, and related disorders. 5. Ongoing medication use that may affect mood or drugs for illnesses associated with mood lability. 6. Subjects who refuse study participation. 7. Other exclusion items: severe physical illness, suicidal ideation, or self-reported current or lifetime major psychiatric disorders (e.g., bipolar disorder, schizophrenia) or prior psychiatric treatments (e.g., anxiolytics, psychotropic medications, psychotherapy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postpartum depression at 6 weeks postpartum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of PPD;Postpartum pain and cumulative consumption of opioids;Postoperative sleep quality;Overall severity of PPB; | — |
Countries
China
Contacts
Public ContactWang Guoqiang
Changzhi Maternal and Child Health Care Hospital
Outcome results
None listed