Skip to content

Effect of Delayed Cord Clamping Combined with Nasal Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia in Preterm Infants: A multicenter randomized controlled trial

Effect of Delayed Cord Clamping Combined with Nasal Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia in Preterm Infants: A multicenter randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127953
Enrollment
Unknown
Registered
2026-07-10
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchopulmonary Dysplasia (BPD)

Interventions

Intervention group:Delayed cord clamping combined with nasal intermittent positive pressure ventilation
Control group:Delayed cord clamping (DCC)

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Mothers delivered in participating study centers; 2. Gestational age was clearly assessed based on the last menstrual period, first-trimester ultrasound, or obstetric evaluation; 3. Mothers received routine perinatal care before delivery; 4. Newborns with a gestational age of 24+0 to 31+6 weeks; 5. Obtained informed consent from the family.

Exclusion criteria

Exclusion criteria: 1. Presence of congenital malformations affecting respiratory function 2. Fetal intrauterine conditions indicating the need for emergency cesarean section, such as umbilical cord prolapse, uterine rupture, etc. 3. Parents refuse to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Bronchopulmonary dysplasia (BPD) incidence;

Secondary

MeasureTime frame
Incidence of intraventricular hemorrhage (IVH > grade 2);Incidence of mortality;Incidence of air leak syndrome;Incidence of necrotizing enterocolitis (NEC >= stage 2) ;Incidence of Retinopathy of Prematurity(ROP);Length of hospital stay;

Countries

China

Contacts

Public ContactHongbo Qi

The First Affiliated Hospital of Chongqing Medical University

qihongbo728@163.com+86 23 63809721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026