Urinary calculi
Conditions
Interventions
Intervention Group:The irrigation solution used during surgery was dilute povidone-iodine
Control Group:The irrigation solution was normal saline
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Unilateral or bilateral ureteral and/or renal stones (>= 5 mm),confirmed by preoperative CT; 3. Failed conservative treatment and require flexible ureteroscopic lithotripsy (URS); 4. capacity to provide written informed consent, willingness to adhere to the protocol, good compliance, and availability for follow-up at the study site;
Exclusion criteria
Exclusion criteria: 1. Patients with a history of iodine allergy; 2. Uncontrolled urinary tract infection (defined as positive nitrite or abundant leukocytes without prophylactic antibiotic administration); 3. Known anatomical abnormalities (e.g., urinary diversion, ureteral stricture); 4. Concurrent urothelial neoplasms; 5. Patients requiring repeat surgery within 3 months due to residual stones; 6. Intraoperative findings that preclude the need for laser lithotripsy (e.g., stones directly retrievable) or failure to access the stone location; 7. Any condition that, in the investigator's opinion, may increase the risk to the subject or interfere with the conduct of the clinical trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual field clarity score;Surgeon's subjective visual field satisfaction score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number and duration of surgery interruptions caused by poor visual field were documented.;Intraoperative adverse reactions to the irrigation solution;Overall complication rate;Stone clearance rate;The number of instances in which the irrigation solution was converted to povidone-iodine to overcome poor visualization in the control group was recorded.;Stone clearance time;Incidence of severe complications; | — |
Countries
China
Contacts
Public ContactPengjie Wu
Beijing Hospital
Outcome results
None listed