sepsis
Conditions
Interventions
Sponsors
Chifeng Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Sepsis group 1.Satisfy the diagnostic criteria of sepsis (presence of infection combined with a SOFA score = 2); 2.ICU admission with definitive diagnosis made within 24 hours. Healthy control group: Healthy volunteers who had health checkups at our hospital during the same period, aged 18 or older, matched with sepsis patients in age and gender, with no history of serious chronic heart, liver, or kidney diseases, and no history of autoimmune diseases or malignant tumors.
Exclusion criteria
Exclusion criteria: 1. Aged under 18 years old; 2. Received long-term (>= 2 weeks) immunosuppressants or glucocorticoids within the past 3 months; 3. Patients with malignant tumors or hematological diseases; 4. Suffering from autoimmune diseases or immunodeficiency disorders; 5. Pregnant or breastfeeding women; 6. Incomplete clinical data or refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pumilio2; | — |
Secondary
| Measure | Time frame |
|---|---|
| SOFA score;Inflammatory factors (TNF-a, IL-6, IL-1ß, etc.);APACHE ? score;duration of mechanical ventilation, vasoactive medication days and CRRT days within Day1–Day28; | — |
Countries
China
Contacts
Public ContactJingjing Zhang
Chifeng Municipal Hospital
Outcome results
None listed