Enlarged tonsils or enlarged adenoids
Conditions
Interventions
The group receiving midazolam intravenously:Intravenous injection of midazolam for sedation
The group receiving remimazolam intravenously:Intravenous injection of remimazolam for sedation
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 1 - 12 years old; 2.ASA I-II; 3.General anesthesia was administered for the elective surgery of tonsil and adenoid removal; 4.The guardian signs the informed consent; children over 8 years old sign the child version of the informed consent;
Exclusion criteria
Exclusion criteria: 1.Allergic to benzodiazepines or related excipients; 2.Severe cardiac and pulmonary dysfunction; 3.Acute respiratory tract infections in the past two weeks; 4.Congenital abnormal liver and kidney function; 5.Neuromuscular diseases, cerebral palsy, epilepsy; 6.Difficult airway; 7.Patients who are expected to require admission to the ICU after the surgery; 8.Participants in other intervention studies that may affect the outcome of this research; 9.Other circumstances that the researchers determined were not suitable for inclusion in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative respiratory adverse events,PRAEs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Separation score;Induction coordination;Degree of sedation; | — |
Countries
China
Contacts
Public ContactLifei Liu
Children's Hospital of Chongqing Medical University
Outcome results
None listed