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Comparison of ultrasound-guided transversus abdominis plane block and rectus sheath block for postoperative analgesia in laparoscopic cholecystectomy: a randomized controlled trial

Comparison of ultrasound-guided transversus abdominis plane block and rectus sheath block for postoperative analgesia in laparoscopic cholecystectomy: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127923
Enrollment
Unknown
Registered
2026-07-09
Start date
2026-07-20
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after laparoscopic cholecystectomy

Interventions

Transversus abdominis plane block group:Bilateral transverse abdominis plane block (TAPB) was performed using 20ml of 0.375% ropivacaine.
Rectus sheath block group:Bilateral rectus abdominis sheath block (RSB) was performed using 20ml of 0.375% ropivacaine.

Sponsors

The First Hospital Of Jiaxing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age between 18 and 65 years; 2.Scheduled for elective laparoscopic cholecystectomy; 3.American Society of Anesthesiologists (ASA) physical status I or II; 4.Signed informed consent;

Exclusion criteria

Exclusion criteria: 1.Presence of mental disorders, cognitive impairment, or language/communication barriers that prevent understanding of the study procedures or completion of pain assessments. 2.Body mass index (BMI) > 35 kg/m^2; 3.Allergy to any of the study medications (especially amide local anesthetics); 4.History of previous abdominal surgery; 5.Contraindications to regional blockade (e.g., coagulopathy, infection at the puncture site, or anatomical abnormalities); 6.Long-term use of opioids or other analgesics; 7.History of chronic pain; 8.Patients with other cardiovascular, cerebrovascular, autoimmune, or neurological diseases; 9.Any other conditions that, in the investigator’s judgment, make the patient unsuitable for the study;

Design outcomes

Primary

MeasureTime frame
NRS score;NRS score;NRS score;NRS score;

Secondary

MeasureTime frame
Incidence of adverse events;Incidence of nausea and vomiting within 24h after operation;Time of first salvage analgesia after operation(time from the end of surgery to the first request for analgesia);Total consumption of postoperative remedial analgesic drugs (within 24h);Postoperative 24-hour recovery quality score;

Countries

China

Contacts

Public ContactChen Yefan

The First Hospital Of Jiaxing

13867726972@qq.com+86 573 86285295

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026