Pain after laparoscopic cholecystectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 65 years; 2.Scheduled for elective laparoscopic cholecystectomy; 3.American Society of Anesthesiologists (ASA) physical status I or II; 4.Signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Presence of mental disorders, cognitive impairment, or language/communication barriers that prevent understanding of the study procedures or completion of pain assessments. 2.Body mass index (BMI) > 35 kg/m^2; 3.Allergy to any of the study medications (especially amide local anesthetics); 4.History of previous abdominal surgery; 5.Contraindications to regional blockade (e.g., coagulopathy, infection at the puncture site, or anatomical abnormalities); 6.Long-term use of opioids or other analgesics; 7.History of chronic pain; 8.Patients with other cardiovascular, cerebrovascular, autoimmune, or neurological diseases; 9.Any other conditions that, in the investigator’s judgment, make the patient unsuitable for the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score;NRS score;NRS score;NRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events;Incidence of nausea and vomiting within 24h after operation;Time of first salvage analgesia after operation(time from the end of surgery to the first request for analgesia);Total consumption of postoperative remedial analgesic drugs (within 24h);Postoperative 24-hour recovery quality score; | — |
Countries
China
Contacts
The First Hospital Of Jiaxing