Intrahepatic cholangiocarcinoma (ICC)
Conditions
Interventions
Observation group:none
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old; 2.Pathologically confirmed as ICC, or highly suspected based on standard imaging evaluation and subsequently confirmed as ICC through pathology/follow-up (pathology is preferred as the gold standard); 3.Complete standardized multi-phase, multi-sequence liver MRI scanning: at least including non-contrast, arterial phase, portal venous phase, delayed phase, T2WI, DWI/ADC; MRCP or hepatobiliary-specific contrast agent hepatobiliary phase (HBP) sequences may be included as enhanced information; 4.The image quality meets the analysis requirements, with no significant motion artifacts or metal artifacts. 5.Complete clinical data: must include at least pathological results, key serological indicators, treatment plans, and follow-up outcome information (OS/DFS/recurrence/metastasis, etc.).
Exclusion criteria
Exclusion criteria: 1.Non-ICC: including hepatocellular carcinoma, metastatic liver tumors, hilar/distal cholangiocarcinoma, and mixed hepatocellular carcinoma, etc. 2.MRI lacks key sequences or has severe artifacts; 3.The differences in image acquisition parameters are extremely large and lack parameter records, making standardized correction impossible. 4.Key clinical outcome data is missing and cannot be supplemented. 5.Pregnant, critically ill, or those who are ethically unsuitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic performance of AI classification model;Generalizability of AI model; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival (OS);Disease-free survival (DFS); | — |
Countries
China
Contacts
Public ContactLiang Xiao
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed