Tourniquet-related Hypotension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective lower-limb surgery under general anesthesia with tourniquet application 2. Age >=60 years 3. ASA physical status I–III
Exclusion criteria
Exclusion criteria: 1. Non-sinus rhythm 2. Known carotid artery stenosis or history of carotid artery surgery 3. BMI > 35 kg/m^2 4. Pre-existing or newly detected carotid artery stenosis > 50% 5. Operation time < 30 min 6. Left ventricular ejection fraction < 50% 7. History of myocardial infarction, overt heart failure, valvular heart disease, or cardiomyopathy 8. Inability to maintain the supine position during the study 9. Refusal to participate in the study by the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tourniquet-related hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vasopressor use after tourniquet deflation;owest blood pressure after tourniquet deflation;AUC for hypotension after tourniquet deflation;Induction hypotension;Postoperative length of hospital stay; | — |
Countries
China
Contacts
General Hospital of Eastern Theater Command