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Research on the Functions and Mechanisms of Neutrophils in Regulating Mesenchymal Stem Cell-Based Bone Tissue Regeneration

Research on the Functions and Mechanisms of Neutrophils in Regulating Mesenchymal Stem Cell-Based Bone Tissue Regeneration

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127884
Enrollment
Unknown
Registered
2026-07-09
Start date
2025-07-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone defect

Interventions

Case group and control group:None

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Inclusion criteria for the case group: (1)closed fracture; (2)no concurrent infection; (3)age >= 18 years; (4)Signed informed consent form; 2.Inclusion criteria for the control group: (1)age and gender matched 1:1 with the case group; (2)healthy individuals with no history of infection, surgery, trauma, or vaccination within the past 3 months; (3)Signed informed consent form

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with thyroid diseases, type I or type II diabetes, or other endocrine disorders; 3. History of tumor surgery, radiotherapy, or chemotherapy; 4. Patients unable to understand the study purpose or unwilling to comply with study requirements; 5. Individuals lacking legal capacity or with limited legal capacity; 6. Any medical history deemed by the investigator as potentially interfering with trial results or increasing patient risk.

Design outcomes

Primary

MeasureTime frame
Proteomics;Complete blood count (CBC);—

Countries

China

Contacts

Public ContactZhang yiming

Shanghai Tenth People's Hospital

Zym811113@tongji.edu.cn+86 137 6171 4733

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026