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Clinical research on the construction and validation of patient awakening prediction threshold rules based on proximal respiratory mechanics characteristics

Development and Validation of a Prediction Model for Tracheal Intubation-Related Movement Events During PACU Emergence Based on Proximal Patient Respiratory Mechanics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127880
Enrollment
Unknown
Registered
2026-07-09
Start date
2026-07-10
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body movement events related to endotracheal tube stimulation during the emergence from anesthesia

Interventions

Gold Standard:A positive event occurs when the patient experiences a body movement.
Index test:Respiratory mechanics characteristics

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18–65 years; 2. Underwent endotracheal intubation with general anesthesia and was transferred to the PACU for observation after surgery; 3. Remained intubated during the awakening phase in the PACU and received standard recovery management; 4. Experienced a clearly defined movement event related to endotracheal intubation stimulation during the awakening period in the PACU.

Exclusion criteria

Exclusion criteria: 1. There were obvious respiratory system diseases or abnormal airway functions before the operation, such as severe chronic obstructive pulmonary disease, acute exacerbation of bronchial asthma, significant restrictive ventilatory dysfunction or upper airway obstruction; 2. There were severe neurological diseases, consciousness disorders or other central nervous system lesions that might affect the assessment of awakening judgment and body movement response; 3. The patient underwent surgeries directly affecting the mechanical characteristics of the respiratory tract, such as lung, trachea, bronchus or other surgeries; 4. The patient continued deep sedation, mechanical ventilation and was transferred to the ICU, without undergoing the routine awakening observation process in the PACU.

Design outcomes

Primary

MeasureTime frame
Discrimination performance;

Secondary

MeasureTime frame
Calibration performance;Clinical net benefit;

Countries

China

Contacts

Public ContactZhang Wensheng

West China Hospital of Sichuan University

975818623@qq.com+86 28 85423237

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026