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The Psychological Intervention for subthreshold depression based on multimodal data

The Psychological Intervention for subthreshold depression based on multimodal data

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127879
Enrollment
Unknown
Registered
2026-07-09
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subthreshold Depression

Interventions

Intervention group:Group Psychotherapy
Waitlist control:None. Waitlist control will not receive psychological counseling during the intervention period and will just continue with their daily life.

Sponsors

Nanjing Normal University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. Current university students aged 18 years or older. 2. Initial screening using the CES-D scale indicating subthreshold depressive symptoms, and suitability for participation confirmed through a one-on-one interview with the research staff. 3. Normal or corrected-to-normal vision and hearing; no color blindness or color weakness. Right-handed. 4. No history of major psychiatric disorders and able to understand the study procedures, complete questionnaires, cognitive tasks, MRI scanning, and hair sample collection. 5. Voluntary participation with signed written informed consent.

Exclusion criteria

Exclusion criteria: 1. Does not meet MRI participation requirements, including but not limited to the presence of metallic implants unsuitable for MRI, pacemakers, claustrophobia, or other MRI contraindications. 2. Color blindness, color weakness, or inability to complete visual emotional stimulus tasks. 3. History of major psychiatric disorders, or current screening/interview indicates prominent psychotic symptoms, risk of manic episodes, severe self-harm or suicide risk, or other conditions unsuitable for participation. 4. Under 18 years of age. 5. Left-handed or ambidextrous. 6. Use of psychiatric medications within the past two weeks. 7. Poor physical condition on the day of the experiment, or in the past three days not suitable for MRI scanning or psychological tasks. 8. Unable to complete the experimental procedures as required, or dropout during the pre- to post-test period, making full participation impossible. 9. Data failing to meet minimum quality standards, such as extensive missing questionnaire data, invalid responses in cognitive tasks, severe head motion or artifacts in MRI data, or missing/untraceable hair sample records.

Design outcomes

Primary

MeasureTime frame
Primary psychological scales;Sleep and emotion-related questionnaires;Neuroendocrine measures;

Secondary

MeasureTime frame
Cognitive-behavioral tasks;MRI measures;

Countries

China

Contacts

Public ContactXinyi Wang

Nanjing Normal University

xinyiwang@njnu.edu.cn+86 157 2062 6172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026