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Pathological analysis, subtype analysis, pathogenic mechanism pathway elucidation, efficacy analysis, and multimodal AI digital diagnosis and treatment development of temporomandibular joint disease

Pathological analysis, subtype analysis, pathogenic mechanism pathway elucidation, efficacy analysis, and multimodal AI digital diagnosis and treatment development of temporomandibular joint disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127874
Enrollment
Unknown
Registered
2026-07-09
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular joint disorder

Interventions

Observation group:None

Sponsors

Department of Stomatology, Third Affiliated Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with temporomandibular joint disorders 2. Patients with temporomandibular joint disorders who agree to have joint lavage fluid, synovial fluid, and blood collected 3. Patients who agree to receive temporomandibular joint treatment 4. Patients who agree to participate in the study and sign written consent 5. Consent from the families of minors 6. Patients treated for malocclusion, cervical spine, lumbar spine, rheumatic joint diseases, etc., at the Third Affiliated Hospital of Southern Medical University from 2025 to 2030

Exclusion criteria

Exclusion criteria: 1. People with other systemic diseases (like cardiovascular issues, blood loss, immune deficiencies, etc.); 2. Patients who are allergic to or cannot take sodium hyaluronate; 3. Patients with special conditions that make TMJ treatment impossible; 4. Except for those currently taking medications that might interfere with TMJ treatment responses.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale Score;MRI image analysis;X ray examination image analysis;Saliva/blood lymphatic marker examination;Spinal and cervical CBCT image analysis;

Countries

China

Contacts

Public ContactXiaomian Wu

Third Affiliated Hospital of Southern Medical University

wuxiaomian898@163.com+86 158 2316 6266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026