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Effect of Early Postnatal Increase in Feeding Volume on Pathological Jaundice in Neonates: A Multicenter Randomized Controlled Trial

Effect of Early Postnatal Increase in Feeding Volume on Pathological Jaundice in Neonates: A Multicenter Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127864
Enrollment
Unknown
Registered
2026-07-08
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pathological jaundice in newborns

Interventions

Control group:Standard feeding
Intervention group:Slightly increased feeding volume based on standard feeding

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
0 Days to 28 Days

Inclusion criteria

Inclusion criteria: 1. Gestational age >= 35 weeks; 2. No need for admission to the neonatal ward after birth; 3. Informed consent from the family obtained before the first feeding.

Exclusion criteria

Exclusion criteria: 1. Congenital malformations; 2. ABO or Rh hemolysis.

Design outcomes

Primary

MeasureTime frame
Incidence of pathological jaundice;—

Secondary

MeasureTime frame
Daily rate of TBil rise;Incidence of feeding intolerance;Peak total serum bilirubin (TBil) level and time to reach peak;Daily weight change;Rate of weight gain;Time to meconium evacuation;Time to resolution of jaundice;—

Countries

China

Contacts

Public ContactHongbo Qi

The First Affiliated Hospital of Chongqing Medical University

qihongbo728@163.com+86 23 63809721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026