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Determination of the minimum effective concentration in 90% of patients (MEC90) of liposomal bupivacaine for ultrasound-guided posterior quadratus lumborum block for postoperative analgesia following laparoscopic unilateral inguinal hernia repair

Determination of the minimum effective concentration in 90% of patients (MEC90) of liposomal bupivacaine for ultrasound-guided posterior quadratus lumborum block for postoperative analgesia following laparoscopic unilateral inguinal hernia repair

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127860
Enrollment
Unknown
Registered
2026-07-08
Start date
2026-07-21
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unilateral inguinal hernia

Interventions

experimental group:Liposomal bupivacaine of different concentrations for ultrasound-guided posterior quadratus lumborum block

Sponsors

The First Hospital Of Jiaxing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status classification I to III; 2. Age ranging from 18 to 85 years old; 3. Body mass index (BMI) between 18 and 30 kg/m^2; 4. The patient or authorized legal representative has signed the surgical and anesthesia informed consent form, fully understands the trial content, voluntarily participates in this study, and signs the trial-specific informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with a history of local anesthetic allergy; 2.Patients with psychiatric or neurological disorders; 3.Severe cardiac,pulmonary,hepatic or renal dysfunction; 4.Patients with contraindications or complications of quadratus lumborum block,such as puncture site infection and coagulation disorders; 5.Patients with a history of chronic pain or preoperative use of sedatives or analgesics; 6.Patients refusing to participate in the trial;

Design outcomes

Primary

MeasureTime frame
MEC90 for successful pain relief within 36 hours after posterior lumbar quadratus lumborum block;

Secondary

MeasureTime frame
NRS score;

Countries

China

Contacts

Public ContactShen Zhangtian

The First Hospital Of Jiaxing

348256268@qq.com+86 573 8251 9999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026