Diabetic foot
Conditions
Interventions
Incident toe ulcer group:No intervention
Non-incident toe ulcer group:No intervention
Sponsors
The Second Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosed with diabetes mellitus and presenting with foot ulceration; 2. Completed baseline foot ASL MRI examination; 3. Available complete clinical and follow-up data; 4. There exists at least one target toe that did not have an ulcer at baseline.
Exclusion criteria
Exclusion criteria: 1. Severe MRI artifacts affecting image analysis; 2. Pre-existing prior amputation of the target toe at baseline; 3. Gout, autoimmune diseases, or other metabolic diseases that may affect foot perfusion assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Baseline toe ASL perfusion volume;Incident toe ulcer;Baseline toe ASL perfusion value;Inter-PLD change in toe perfusion parameters;Area under the receiver operating characteristic curve;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline data (Age, sex, diabetes duration, HbA1c, fasting blood glucose, diabetic peripheral neuropathy, peripheral artery disease, and diabetic kidney disease); | — |
Countries
China
Contacts
Public ContactYe Junliang
The Second Affiliated Hospital of Guangxi Medical University
Outcome results
None listed