Tachycardia, bradycardia, hypotension, hypertension, hypoxemia, intraoperative agitation, excessive sedation, laryngospasm, bronchospasm, nausea, vomiting, reflux aspiration, severe allergic reaction, etc
Conditions
Interventions
Group Oliceridine(Group OG):Intravenous Oliceridine was administered as an analgesic for intravenous anesthesia
Group Fentanyl(Group FG):Intravenous Fentanyl was administered as an analgesic for intravenous anesthesia
Sponsors
Jiangmen Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Between 18 and 65 years, gender is unlimited; 2. Patients with middle and lower ureteral segments, bladder and urethral stones, and undergoing elective surgery for transurethral endoscopic lithotripsy and lithotomy; 3. ASAI-? level; 4. The estimated operation time was 60min; 5. Informed consent, volunteered to participate in the trial, and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergic to the trial drug; 2. Abnormal abnormalities: QT interval greater than 450 ms in men and greater than 470 ms in women; 3. Cognitive impairment or language ability was unable to complete the study questionnaire; 4. Pregnant or lactating women; 5. History of drug abuse, drug use and alcohol abuse in the preceding two years; 6. Have participated in other drug or device clinical trials within 3 months prior to the screening period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of recovery on the first postoperative day (QoR-15); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence rate of intraoperative respiratory and circulatory adverse events;Body movement grading;length of stay;Surgeon satisfaction;Utilization rate of respiratory assistance measures;Postoperative separation time; | — |
Countries
China
Contacts
Public ContactLin Huafu
Jiangmen Central Hospital
Outcome results
None listed