Erosive oral lichen planus
Conditions
Interventions
Experimental group:Topical beta-carotene gel group
Sponsors
Beijing Bo'ai Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with erosive OLP by the Department of Dentistry of China Rehabilitation Research Center; 2. A single erosive area of >= 1 square centimeter, or multiple erosive areas with a total area of >= 1 square centimeter, or an erosive area of = 1 square centimeter; 3. The disease course is >= 6 months; 4. There has been repeated recurrence after local treatment with glucocorticoids; 5. Voluntary for follow-up.
Exclusion criteria
Exclusion criteria: 1. Those with a history of severe allergies or specific constitutions (BC); 2. Those who have received systemic treatment within the last 3 months or local treatment within 2 weeks before enrollment; 3. Those with complications such as uncontrolled hypertension, cardiovascular diseases, blood disorders, neurological and mental disorders, or other systemic diseases that require medication; 4. Those with lichenoid lesions caused by amalgam fillings or certain medications; 5. Pregnant women, lactating women, or women of reproductive age who refuse contraception during the study observation period; 6. Oral external flat lentigo lesions; 7. Other oral mucosal diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in oral mucosal lesions before and after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory cytokine levels;Quality of life and incidence of adverse events; | — |
Countries
China
Contacts
Public ContactWang Xing
Beijing Bo'ai Hospital
Outcome results
None listed