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Construction of an evaluation system for the cardiac safety of anti - tumor drugs based on multi - modal data models

Construction of an evaluation system for the cardiac safety of anti - tumor drugs based on multi - modal data models

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127818
Enrollment
Unknown
Registered
2026-07-08
Start date
2026-07-08
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant solid tumors (lung cancer, breast cancer, gastrointestinal cancer, ovarian cancer, etc.), antineoplastic drug-related cardiotoxicity (myocardial injury, cardiac dysfunction, arrhythmia, heart failure, etc.)

Interventions

Antineoplastic drug treatment group:None

Sponsors

Harbin Medical University Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Diagnosed with solid malignant tumors (including lung cancer, breast cancer, gastrointestinal tumors, ovarian cancer, etc.) by pathological histology or cytology, and received anti - tumor drug treatments such as chemotherapy, targeted therapy, and immunotherapy in our hospital from January 2020 to December 2025; 2.The baseline data of cardiac function is complete, and the patient can cooperate to complete cardiac-related examinations such as electrocardiogram and echocardiogram. 3.The clinical data, medication records, and follow - up information are complete, which can meet the requirements for multi - modal data collection and analysis.

Exclusion criteria

Exclusion criteria: 1.Those who have combined severe primary heart diseases (such as refractory heart failure, severe arrhythmia, acute myocardial infarction, etc.) and cannot tolerate anti - tumor treatment. 2.Patients with mental illness or cognitive impairment who are unable to cooperate with the collection and monitoring of research data. 3.Those with severely missing clinical data and unable to be included in the data model analysis;

Design outcomes

Primary

MeasureTime frame
Antineoplastic drug-related cardiotoxicity;

Countries

China

Contacts

Public ContactDong Mei

Harbin Medical University Cancer Hospital

13804567370@163.com+86 451 86298880

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026