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Comparison of aberration-guided vs standard Fs-LASIK for high corneal aberrations

Comparison of Refractive Correction and Visual Quality Between Corneal Aberration-Guided and Standard FS-LASIK in Patients with High Corneal Aberrations: A Clinical Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127807
Enrollment
Unknown
Registered
2026-07-08
Start date
2026-07-31
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High corneal aberrations combined with refractive error (myopia with or without astigmatism)

Interventions

CWG FS-LASIK group:Corneal Wavefront-Guided FS-LASIK (CWG FS-LASIK)
Standard FS-LASIK (AF mode):Standard FS-LASIK (AF mode)

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged 18-35 years planned for FS-LASIK surgery; 2.Minimum preoperative corneal thickness >= 480 µm, residual postoperative corneal stromal bed thickness >= 300 µm; 3.Myopia: -1.00 D to -9.00 D, Astigmatism = 1.0 (LogMAR = 0.25 µm and total higher-order aberrations RMS >= 0.4 µm (measured by Keratron Scout corneal topographer);

Exclusion criteria

Exclusion criteria: 1.Active ocular disease; 2.Keratoconus or suspicious changes on corneal topography; 3.History of ocular surgery or trauma; 4.Pregnancy or lactation;

Design outcomes

Primary

MeasureTime frame
Corneal aberration;Ocular aberration;Uncorrected distant visual acuity;—

Secondary

MeasureTime frame
Spherical Equivalent;Best-corrected distant visual acuity;10% low-contrast visual acuity;—

Countries

China

Contacts

Public ContactKe Ma

West China Hospital of Sichuan University

280463919@qq.com+86 28 85422536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026