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Effectiveness of an Electronic Medication Monitoring System to Improve Antipsychotic Adherence Among Community-Dwelling Individuals With Schizophrenia: A Type 1 Effectiveness–Implementation Hybrid Randomized Controlled Trial

Using Electronic Pillboxes to Improve Medication Adherence in Schizophrenia Patients - A Formal Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127803
Enrollment
Unknown
Registered
2026-07-08
Start date
2026-07-20
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Intervention group:Participants will receive a functional MEMS pillbox capable of real-time recording and cloud upload of pillbox-opening events, along with scheduled musical reminders. Village doctor
Control group:Participants will receive an identical pillbox with all electronic functions disabled and will continue to receive usual community-based mental health care.

Sponsors

Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Diagnosis of schizophrenia based on ICD-10; 3. Registered in SMIMS; 4. Currently prescribed oral antipsychotic medication; 5. Resident in selected townships of Yunnan; 6. Able to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Currently hospitalized; 2. Has failed to collect medication for >=3 consecutive months; 3. Severe visual or hearing impairments preventing MEMS use.

Design outcomes

Primary

MeasureTime frame
Medication Adherence–Daily Rate;

Secondary

MeasureTime frame
Medication adherence (BARS-based);Drug Attitude;Symptom Severity;Functional Status;Medication Side Effects;Acceptability/Appropriateness/Feasibility;Adoption;Penetration;Fidelity;Sustainability;Cost;

Countries

China

Contacts

Public ContactDong (Roman) Xu

Southern Medical University

romanxu@gmail.com+86 139 1098 8979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026