The incidence of MINS within 72 hours after surgery. MINS is defined as an increase in postoperative cTn levels due to potential ischemic mechanisms without any obvious non-ischemic causes (such as pulmonary embolism), with at least one cTn concentration exceeding the 99th percentile of the normal population reference range.
Conditions
Interventions
TEAS group:Perioperative sequential TEAS
The sham TEAS group:No current is connected, no irritation
Sponsors
The First Hospital of Jiaxing
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years old, gender not restricted; 2. Scheduled unilateral hip or knee joint replacement under general anesthesia; 3. ASA classification I - III; 4. Preoperative hs-cTnI within the normal reference range; 5. Voluntary participants who have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who experienced acute coronary syndrome, acute myocardial infarction, decompensated heart failure (NYHA grade IV) or malignant arrhythmia within 30 days before the surgery; 2. Patients whose preoperative cTn level was higher than the normal range, or who had severe infection, severe liver or kidney dysfunction; 3. Patients who had implanted cardiac pacemakers, implantable cardioverter-defibrillators or other electronic devices; 4. Patients with damaged, infected, severe scarring skin at the acupuncture stimulation site or who were allergic to electrode patches; 5. Patients with malignant tumors, coagulation dysfunction; 6. Patients with mental disorders, cognitive impairment or other reasons that prevented them from cooperating with acupuncture stimulation and follow-up; 7. Patients who refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| What happens within 72 hours after the operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse cardiovascular reactions include new-onset arrhythmias and hypotension.;QoR-15 scale; | — |
Countries
China
Contacts
Public ContactDeng Kang
The First Hospital of Jiaxing
Outcome results
None listed