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Effect of Oral and Airway Secretion Clearance on Late-Onset Sepsis in Preterm Infants: A Multicenter Randomized Controlled Trial

Effect of Oral and Airway Secretion Clearance on Late-Onset Sepsis in Preterm Infants: A Multicenter Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127784
Enrollment
Unknown
Registered
2026-07-07
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

late-onset sepsis (LOS)

Interventions

Control group:Negative-Pressure Suction Method
Intervention group:Swab Wiping Method

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Newborns with a gestational age of 24+0 to 31+6 weeks; 2. Require oral suctioning after admission; 3. Obtained informed consent from their parents or legal guardians.

Exclusion criteria

Exclusion criteria: 1. Has a serious congenital disease; 2. The parents refuse to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
Late-Onset Sepsis(LOS);—

Secondary

MeasureTime frame
Incidence of Retinopathy of Prematurity (ROP);Incidence of grade III–IV intraventricular hemorrhage (IVH) (according to Papile criteria);Bronchopulmonary dysplasia (BPD) incidence (according to the 2001 and 2019 criteria);Total duration of mechanical ventilation;Length of hospital stay;Incidence of oral mucosal injury;Total duration of antibiotic use;Incidence of necrotizing enterocolitis (NEC) (according to Bell's staging criteria);—

Countries

China

Contacts

Public ContactQi Hongbo

The First Affiliated Hospital of Chongqing Medical University

qihongbo728@163.com+86 23 63809721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026