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Clinical Observation of Lidocaine Nebulization for Relieving Sore Throat after Thyroid Surgery

Lidocaine Nebulization for Prophylaxis and Treatment of Post-Thyroidectomy Sore Throat

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127772
Enrollment
Unknown
Registered
2026-07-07
Start date
2026-07-16
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat after thyroid cancer surgery

Interventions

Test group:Lidocaine nebulization
Control group:Saline nebulization

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with thyroid carcinoma who underwent unilateral lobectomy or total thyroidectomy under general anesthesia with tracheal intubation; 2. Aged 18 to 70 years old; 3. American Society of Anesthesiologists (ASA) physical status classification grade ?–?.

Exclusion criteria

Exclusion criteria: 1. Patients with preexisting sore throat or pharyngitis before surgery; 2. Patients with upper respiratory tract infection within the previous 2 weeks; 3. Patients diagnosed with chronic obstructive pulmonary disease (COPD); 4. Pregnant patients; 5. Patients with allergy or contraindications to the study drug; 6. Difficult airway with Mallampati classification grade > 2; 7. Patients with a history of oral, nasal or head and neck surgery; 8. Patients undergoing lateral cervical lymph node dissection (levels II-V); 9. Patients requiring more than one intubation attempt, or those experiencing surgical or anesthetic complications intraoperatively or postoperatively; 10. Patients with tracheal invasion by tumor requiring combined tracheal resection; 11. Patients with intraoperative recurrent laryngeal nerve invasion or injury by tumor.

Design outcomes

Primary

MeasureTime frame
The severity of patients' throat pain;

Secondary

MeasureTime frame
hoarseness;cough;

Countries

China

Contacts

Public ContactYe Yusheng

The First Affiliated Hospital of Anhui Medical University

yeyusheng@fy.ahmu.edu.cn+86 551 6323 6406

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026