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Milk temperature reducing necrotizing enterocolitis in preterm infants: A multicenter randomized controlled trial

Milk temperature reducing necrotizing enterocolitis in preterm infants: A multicenter randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127768
Enrollment
Unknown
Registered
2026-07-07
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal necrotizing enterocolitis

Interventions

Control group:None
Experimental group:Warmed pump feeding

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Gestational age < 32 weeks 2. Initiation of enteral nutrition within 24 hours after birth

Exclusion criteria

Exclusion criteria: 1. The family members refused to participate in the study. 2. There are significant congenital malformations. 3. Surgical intervention was required before random grouping.

Design outcomes

Primary

MeasureTime frame
Incidence of necrotizing enterocolitis (NEC = stage 2) (according to the Bell staging criteria);

Secondary

MeasureTime frame
Incidence of late-onset sepsis (LOS);Incidence of extrauterine growth restriction (EUGR);Incidence of feeding intolerance;Time to full enteral feeding;Incidence of retinopathy of prematurity (ROP > stage II);Weekly weight gain;Incidence of intraventricular hemorrhage (IVH > grade 2) (according to the Papile classification);Bronchopulmonary dysplasia (BPD) incidence (defined according to the 2001 and 2019 criteria);

Countries

China

Contacts

Public ContactQi Hongbo

The First Affiliated Hospital of Chongqing Medical University

qihongbo728@163.com+86 23 6380 9721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026