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Effects of Transcranial Direct Current Stimulation Targeting the Ventromedial Prefrontal Cortex on Physical and Social Pain Perception in Healthy Adults

Effects of Anodal Transcranial Direct Current Stimulation Targeting the Ventromedial Prefrontal Cortex on Different Types of Pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600127767
Enrollment
Unknown
Registered
2026-07-07
Start date
2026-07-15
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

Anodal Stimulation:Each participant needs to complete two experimental conditions: anodal stimulation and sham stimulation, with a washout period of at least 7 days after finishing the first condition

Sponsors

Shenzhen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Healthy adults aged 18–50 years; 2. Right-handed; 3. No implanted metallic materials, including metallic dental braces or dentures; 4. Normal or corrected-to-normal vision (with proper prescription glasses or other interventions); 5. No contraindications to transcranial electrical stimulation or heat pain stimulation; 6. Able to understand the study procedures, willing to participate, and able to provide informed consent; 7. No participation in interventional neuromodulation studies, including transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), or transcranial alternating current stimulation (tACS), within one month prior to enrollment.

Exclusion criteria

Exclusion criteria: 1. History of cardiovascular or cerebrovascular disease, severe respiratory disease, or other severe physical illness; 2. History of neurological disease or brain injury; 3. History of psychological or psychiatric disorders; 4. History of psychoactive substance use disorder or drug dependence, or current use of medications that may affect central nervous system function, pain perception, or emotional state; 5. Recent use of psychiatric medications; 6. History of Chronic pain; 7. Participants deemed unsuitable for this study by clinical researchers.

Design outcomes

Primary

MeasureTime frame
Pain Intensity;Unpleasantness;Exclusion/Inclusion;

Countries

China

Contacts

Public ContactXiaoyun Li

Shenzhen University

lxyevelynli@gmail.com+86 131 0696 9670

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026