Diffuse large B-cell lymphoma.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Diagnosed as DLBCL through histopathological examination, using the classification system of the World Health Organization (WHO); 2. Has not previously received treatment for DLBCL; 3. The projected lifespan exceeds 3 months; 4. 18<=age=<75 years, with no gender restrictions; 5. The absolute neutrophil count should be at least 500/µL, and the platelet count should be at least 50,000/µL; 6.If the subject is of reproductive age, effective contraceptive measures must be employed, and they must agree to comply with all contraceptive requirements; 7.The observer signed the informed consent form for the experimental treatment.
Exclusion criteria
Exclusion criteria: 1.Women who are pregnant or breastfeeding (breastfeeding women must agree not to breastfeed while taking pomalidomide); 2.Individuals known to be allergic to the components of the experimental drug; 3.Combine severely affected individuals; 4. The researcher considers the individual unsuitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate at the end of induction therapy.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective response rate at the end of maintenance therapy.;PFS;OS;DOR; | — |
Countries
China
Contacts
Henan Cancer Hospital