Infectious diseases
Conditions
Interventions
Infectious Disease Observation Group:None
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Source of the strains: From January 1, 2022 to December 31, 2024, non-repetitive VREfm strains were isolated from various clinical specimens (such as blood, urine, secretions, etc.) in the microbiology laboratory of Yuebei People's Hospital. 2. Patient information: Traceable to the corresponding anonymized inpatient information.
Exclusion criteria
Exclusion criteria: 1. Repeated strains isolated from the same patient within 30 days (only the first strain is included); 2. Strains that could not be revived due to improper preservation or poor quality of DNA extraction; 3. The corresponding patient's clinical medical records are severely lacking, making it impossible to obtain basic demographic and key clinical information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All kinds of drug resistance genes (vanA/B/M, etc.) and virulence genes (esp, acm, etc.) in VREfm strains Prevalence rates and their co-occurrence patterns; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of MDR-HV clones such as vanA+esp+acm+ detected in VREfm strains;Dominant ST types and their distribution frequencies of VREfm in northern Guangdong People's Hospital;Homologous clonal clusters (<=5 SNP differences and spatio-temporal association) identified based on SNP analysis of the core genome Quantity and Characteristics; | — |
Countries
China
Contacts
Public ContactHelin Zhang
Yuebei People’s Hospital
Outcome results
None listed