Dentition defect with insufficient buccal keratinized mucosa width at the implant site
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged >= 18 years old, in good general health condition; 2.Patients with dentition defect scheduled for implant restoration, with buccal keratinized mucosa width (KMW) = 7 days and indicators return to normal; 6.Patients provide informed consent and sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women; 2.Surgical site adjacent to the mental foramen, requiring simultaneous bone augmentation surgery, or with previous history of mucosal gingival graft surgery; 3.History of head and neck radiotherapy; 4.Complicated with uncontrolled diabetes mellitus, immunodeficiency, coagulation disorders, malignant tumors and other systemic diseases affecting tissue healing; 5.Taking anticoagulant or antiplatelet drugs within 3 months before surgery; 6.Heavy smoking (>= 10 cigarettes per day).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Net gain of keratinized mucosa width at 7 months postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| SEM microstructure parameters of CGF membrane;TGF-ß1 release level of CGF membrane;Mechanical properties of CGF membrane; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital