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The Role of the Gonadal Microenvironment in Regulating Reproductive Health and Strategies for Intervention

The Role of the Gonadal Microenvironment in Regulating Reproductive Health and Strategies for Intervention

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127749
Enrollment
Unknown
Registered
2026-07-07
Start date
2026-07-20
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertile

Interventions

Abnormalities in the fallopian tubes and uterine cavity environment:None
No abnormalities were found in the fallopian tubes or through the hysteroscopy(Standard Group):None

Sponsors

Chongqing Health Center for Women and Children
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 40 Years

Inclusion criteria

Inclusion criteria: The female patients are aged 25-40 and need to undergo fallopian tube and hysteroscopy exams, with normal chromosomal tests for both partners. 1. Standard group patients: Infertility caused by male sperm issues, such as oligospermia or weak sperm, while the female partner has no abnormalities in fallopian tube or hysteroscopy exams. 2. Patients with abnormal uterine cavity environment (thin endometrium, recurrent miscarriage): (1) At least one failed IVF/ICSI-ET/FET transfer; (2) Endometrial thickness less than 7 mm after natural cycle or hormone replacement therapy (HRT); (3) Repeated checks showing thin endometrium and no abnormalities in hysteroscopy within the past six months. 3. Patients with fallopian tube abnormalities: Fallopian tube blockage/obstruction, hydrosalpinx, congenital malformations, etc.

Exclusion criteria

Exclusion criteria: 1.Standard group patients: Abnormalities were observed during the examination of the fallopian tubes and the uterine cavity.

Design outcomes

Primary

MeasureTime frame
Key metabolic factors;

Countries

China

Contacts

Public ContactMo Chen

Chongqing Health Center for Women and Children

17501641476@163.com+86 23 6035 4393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026