Pneumonia
Conditions
Interventions
Sponsors
Chongqing University Three Gorges Hospital(Chongqing Three Gorges Central Hospital)
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years old; 2.Admission due to pneumonia-like symptoms or main manifestations during the course of the disease being pulmonary infection-like changes; 3.Presence of patchy shadows, consolidation shadows, ground-glass shadows, subpleural lesions, pleural effusion or migratory pulmonary lesions on chest CT; 4.During the course of the disease, objective examinations have confirmed the presence of deep vein thrombosis in the lower extremities, pulmonary embolism or other venous thromboembolic events; 5.Antiphospholipid antibody panel tests have been completed or are planned to be completed, including lupus anticoagulant, anticardiolipin antibody and anti-ß2 glycoprotein I antibody; 6.Basic completeness of clinical data, laboratory test data, imaging data and treatment outcome data; 7.The patient or their legal representative has agreed to participate in the study; for retrospective data studies, if informed consent cannot be obtained, an application for informed consent exemption should be made after approval by the ethics committee.
Exclusion criteria
Exclusion criteria: 1.Clinical data is severely lacking, making it impossible to determine whether the symptoms resemble pneumonia, whether there are thrombosis events, or the status of antiphospholipid antibodies; 2.If the lung lesions have a clear non-APS-related cause and can fully explain the condition, such as clear cases of pulmonary tuberculosis, pulmonary fungal diseases, lung malignancies, pulmonary vascular malformations, etc.; 3.If there are clear recent major surgeries, severe traumas, long-term bed rest, active malignant tumors, etc. as strong triggers, and the clinical judgment is that the thrombosis is mainly caused by these factors; 4.If a hereditary tendency for thrombosis has been diagnosed, and the relationship with this thrombosis event is more clear; 5.Pregnant or postpartum patients can be analyzed separately based on the research design. If this study is limited to non-obstetric APS, they should be excluded; 6.If there are severe liver and kidney failure, disseminated intravascular coagulation, or other serious coagulation system diseases that affect the interpretation of antiphospholipid antibodies and coagulation indicators; 7.Other situations that the researcher considers not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower extremity venous thrombosis, pulmonary artery thrombosis, and changes in related antibodies; | — |
Countries
China
Contacts
Public ContactXu Gang
Chongqing University Three Gorges Hospital(Chongqing Three Gorges Central Hospital)
Outcome results
None listed