Schizophrenia
Conditions
Interventions
SCZ group:None
Sponsors
Wuxi Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for SCZ Group: 1. Meet the diagnostic criteria for SCZ according to DSM-5. 2. Have no history of brain injury, organic brain diseases, or other severe physical illnesses. 3. Have not used medications affecting cognitive function within 2 weeks prior to enrollment, and have no history of psychoactive substance use. 4. Be of Chinese Han ethnicity, both males and females, aged between 18 and 65 years, with an education level of junior high school or above. 5. Have normal visual acuity or corrected-to-normal vision, and no color blindness. 6. Voluntarily participate in this study. Inclusion Criteria for HC Group: 1. Do not meet diagnostic criteria for any mental disorder and have no family history of mental disorders. 2. Be of Chinese Han ethnicity, both males and females, aged between 18 and 65 years, with an education level of junior high school or above. 3. Have normal visual acuity or corrected-to-normal vision, and no color blindness. 4. Voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: SCZ group: 1. Meet other DSM-5 diagnoses, such as depressive disorder, bipolar disorder, etc.; 2. Have a history of craniocerebral trauma with loss of consciousness, epilepsy, or uncontrolled severe physical diseases (e.g., coronary heart disease, thyroid dysfunction) that make it difficult to complete clinical data collection; 3. Have received electroconvulsive therapy (ECT) or modified ECT within the past 6 months; 4. Are pregnant or lactating women, or persons planning to conceive; 5. Have uncorrectable visual/auditory impairment that cannot be restored to basically normal function; 6. Have obvious finger motor dysfunction (unable to click a mouse or write); 7. Do not agree to sign the informed consent form. HC group: 1. Have a history of craniocerebral trauma with loss of consciousness, epilepsy, or uncontrolled severe physical diseases (e.g., coronary heart disease, thyroid dysfunction) that make it difficult to complete clinical data collection; 2. Have obvious cognitive dysfunction; 3. Are pregnant or lactating women, or persons planning to conceive; 4. Have uncorrectable visual/auditory impairment that cannot be restored to basically normal function; 5. Have obvious finger motor dysfunction (unable to press keys); 6. Do not agree to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurophysiological characteristics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Behavioral data (accuracy rate, reaction time, error types);General information (Demographic data collection (including age, gender, ethnicity, occupation, marital status, educational level, portability, years of education, etc.);Positive and Negative Symptom Scale (PANSS);SANS Scale;SANS Scale;Epidemiological data (including age of onset, disease course, past medical history, family history, smoking history, alcohol and psychotropic drug use, etc.); | — |
Countries
China
Contacts
Public ContactFan Zhen
Wuxi Mental Health Center
Outcome results
None listed