Non-lactational mastitis (NLM)
Conditions
Interventions
Control group:None
Sponsors
Fuzhou University Affiliated Provincial Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Confirmed diagnosis of NLM by core needle biopsy or postoperative histopathological examination, including two pathological subtypes: granulomatous lobular mastitis (GLM) and periductal mastitis (PCM), with pathological diagnosis consistent with relevant international diagnostic criteria; 2.Non-lactating females aged 18–60 years; 3.No treatment-related contraindications such as rifampicin allergy or coagulation dysfunction; 4.No response to standardized treatment with glucocorticoids, antibiotics, and other medications for more than 4 weeks, with a disease course exceeding 2 months; 5.Complete clinical medical records and ability to complete standardized follow-up for at least 12 months.
Exclusion criteria
Exclusion criteria: 1.Tuberculous mastitis and inflammatory breast cancer; 2.Pregnant or lactating females; 3.Patients with severe coagulation disorders or vital organ insufficiency; 4.Breast implant placement; 5.Patients lost to follow-up or with incomplete data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete remission rate;Recurrence rate;Lesion Volume Reduction Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complication rate; | — |
Countries
China
Contacts
Public ContactYang Jianchuan
Fuzhou University Affiliated Provincial Hospital
Outcome results
None listed