Parkinson's disease, all-cause mortality in Parkinson's disease patients
Conditions
Interventions
Group:Non-Parkinson's disease control group:None
Parkinson's disease case group:None
Sponsors
Wenzhou People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for case group: (1) Meet the UK Brain Bank clinical diagnostic criteria for Parkinson’s disease; (2) Complete routine blood tests, comprehensive biochemical panel, and electrolyte laboratory tests upon admission; (3) Have complete baseline medical records with traceable follow-up data on post-discharge all-cause mortality; (4) Medical records must be de-identified. 2. Inclusion criteria for control group: (1) Hospitalization period concurrent with that of the case group; (2) No history of Parkinson’s disease, Parkinson-plus syndromes, or secondary parkinsonism; (3) Complete routine blood tests, biochemical panel, and electrolyte tests upon admission; (4) Have complete baseline clinical data.
Exclusion criteria
Exclusion criteria: 1. All types of secondary parkinsonism, Parkinson-plus syndromes, and hereditary Parkinson's disease; 2. Complicated with malignant tumors, end-stage liver and renal failure, or severe hematological diseases before enrollment; 3. Received treatments that could significantly affect peripheral blood test results such as blood transfusion or high-dose hormone pulse therapy within 1 month prior to admission; 4. Massive missing key indicators of routine blood tests, biochemistry and electrolytes, making statistical analysis unavailable; 5. Incomplete clinical data that prevents the judgment of follow-up outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parkinson's disease status; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality; | — |
Countries
China
Contacts
Public ContactHua Ye
Wenzhou People's Hospital
Outcome results
None listed