Perioperative anxiety of cesarean section patients
Conditions
Interventions
Non-anxious group:The starting dose of remimazolam is 0.1 mg/kg, with a dose increment set at 0.01 mg/kg. If sedation is successful, the dose for the next patient is reduced by 0.01 mg/kg
if sedation fails, the dose for the next patient is increased by 0.01 mg/kg.
Anxiety group:The starting dose of remimazolam is 0.1 mg/kg, with a dose increment set at 0.01 mg/kg. If sedation is successful, the dose for the next patient is reduced by 0.01 mg/kg
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Age 18~ 45 years old; 2.ASA classification grade II; 3.Single-term women undergoing elective cesarean section;
Exclusion criteria
Exclusion criteria: 1.Maternal refusal; 2.There's an infection at the puncture site; 3.Serious abnormality of coagulation function; 4.Spinal trauma; 5.Allergy to remazolam or contraindications to use; 6.Impaired preoperative consciousness or long-term use of antidepressants and psychiatric drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The median effective effect-concentration;The 95% effective effect-concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal satisfaction;Hypotension;Hypertension;Hyoxemia;Bradycardia;Nausea;vomiting; | — |
Countries
China
Contacts
Public ContactZhenhua Nan
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed