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A Retrospective Cohort Study on the Effect of Preoperative Nutritional Risk on Anastomotic Leakage After Radical Resection for Gastrointestinal Cancer

A Retrospective Cohort Study on the Effect of Preoperative Nutritional Risk on Anastomotic Leakage After Radical Resection for Gastrointestinal Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600127637
Enrollment
Unknown
Registered
2026-07-03
Start date
2026-07-31
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer, colon cancer, rectal cancer

Interventions

Sponsors

Wuxi people’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Pathological examination after surgery confirmed primary stomach cancer or colorectal cancer; 2. Underwent elective radical surgery with digestive tract anastomosis reconstruction during the operation (including D2 radical gastrectomy for stomach cancer, radical colectomy for colon cancer, total mesorectal excision for rectal cancer); 3. Completed a standard NRS2002 nutrition risk screening within 24 hours of admission, with complete and traceable scoring data; 4. Clinical records, surgical anesthesia records, lab tests, imaging data, and postoperative follow-up information are all complete.

Exclusion criteria

Exclusion criteria: 1. Emergency surgeries, palliative surgeries, bypass surgeries, simple exploratory surgeries, or cases where radical resection and gastrointestinal anastomosis were not performed; 2. Patients who received neoadjuvant radiotherapy, chemotherapy, or chemoradiotherapy before surgery; 3. Patients with severe heart, liver, kidney, or lung dysfunction, autoimmune diseases, blood system diseases, or active infections; those with a history of major abdominal or gastrointestinal surgery that could affect postoperative outcome evaluation; 4. Patients lost to follow-up during the perioperative period, or cases with incomplete clinical data, NRS2002 screening data, or postoperative outcome data. Data quality control: all data were extracted by dedicated personnel from previous clinical information systems, using double-checking and cross-review methods to ensure data are true, accurate, and complete; 5. Before the retrospective analysis, data were cleaned, anonymized, and quality controlled again. Any missing, abnormal, or inconsistent data were verified against the original medical records to ensure reliable study results.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative anastomotic leakage;

Secondary

MeasureTime frame
Length of hospital stay and hospitalization costs;Postoperative infectious complications;Severity of anastomotic leakage;Severe complications of Clavien-Dindo grade III and above;

Countries

China

Contacts

Public ContactTian Zhiqiang

Wuxi people’s Hospital

zhiqiangtiann@163.com+86 510 85350091

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026