Postoperative fatigue after thoracoscopic pulmonary resection
Conditions
Interventions
SGB group:stellate ganglion block(SGB)
Control group:Procedural sham block
Sponsors
Huai'an First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective thoracoscopic pulmonary resection (segmentectomy or lobectomy) under general anesthesia with tracheal intubation; 2. American Society of Anesthesiologists (ASA) physical status classification ?–? before surgery; 3. Patients aged 18 to 75 years; 4. Capable of understanding and finishing scale assessments (with neutral explanation provided by researchers when necessary); 5. Body mass index (BMI): 18.5–30.0 kg/m²; 6. Voluntarily participate in this trial and sign the informed consent form. 7. Additional inclusion requirement: Subjects shall complete preoperative scale assessments (ICFS-10, AIS, QoR-15) and be available for follow-up at postoperative day 1, 3 and 7.Exclusion note: Patients with anticipated postoperative ICU admission, difficult extubation or prolonged postoperative sedation are excluded from enrollment.
Exclusion criteria
Exclusion criteria: 1. Unable to understand or refuse to sign the informed consent form. 2. Presence of severe combined cardiac, hepatic or pulmonary complications and surgical contraindications. 3. Presence of severe respiratory diseases (asthma, chronic obstructive pulmonary disease), dysfunction of other vital organs, coagulation disorders or infection at the puncture site. 4. Presence of severe central nervous system or psychiatric disorders (such as major depression, acute psychotic symptoms, recent suicidal risk, etc.). 5. Continuous use of anesthetic analgesics, sedatives or nonsteroidal anti-inflammatory drugs for >=2 weeks, or use for >=15 days within the past 30 days. Patients taking high-dose hypnotics or at risk of hypnotic dependence will be excluded; for other patients, baseline medication status will be recorded and adjusted in analyses. 6. Hearing or verbal communication impairment that prevents effective communication with clinicians. 7. Judged by the investigator to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ICFS-10 scores on postoperative days 1, 3, and 7, and the postoperative fatigue trajectory over time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative and postoperative hemoglobin and albumin;Postoperative sleep quality;Time to first oral intake after surgery, time to first ambulation after surgery;Postoperative pain score;The length of postoperative hospital stay and readmission status within 30 days after discharge were recorded;Postoperative opioid consumption;Incidence of postoperative adverse reactions (including drowsiness, nausea, vomiting, etc);Postoperative recovery quality score;Intraoperative vasoactive drug consumption;Intraoperative hemodynamic parameters;Incidence of postoperative complications (including pneumonia, atelectasis, reintubation, reoperation, and pleural effusion requiring puncture drainage); | — |
Countries
China
Contacts
Public ContactZheng Ying
Huai'an First People's Hospital
Outcome results
None listed