Procedural sedation and analgesia in Children with Autism Spectrum Disorder
Conditions
Interventions
Propofol-eskatemine (PS group):Propofol 2 mg/kg + eskatemine 0.30 mg/kg
Ciprofol-eskatemine (CS group):Cirprofol 0.4 mg/kg + eskatemine 0.30 mg/kg
Sponsors
Sir Run Run Hospital Nanjing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Those who meet the corresponding surgical indications; 2. Those with ASA II-III; 3. Those aged 2 to 14 years old; 4. Those whose guardians have given full informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to the test drug or have contraindications; 2. Patients with severe kidney, liver, neurological or cardiovascular diseases; 3. Children with diseases related to increased intracranial pressure; 4. Children with upper respiratory tract infections, tracheitis, bronchitis, or pulmonary infections, and are expected to have difficult airways; 5. Those who have used anesthetic or sedative drugs recently; 6. Children whose parents have signed to refuse participation in the study are not included in the scope of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of intraoperative body movement; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total dosage of propofol or ciprofol;The number of additional doses of propofol or ciprofol;Anesthesia recovery time; | — |
Countries
China
Contacts
Public ContactMiao Yanxiang
Sir Run Run Hospital Nanjing Medical University
Outcome results
None listed